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Osmotic Pressure | Colligative Properties Class 12

Osmotic Pressure | Colligative Properties Class 12

Osmotic Pressure

Colligative Properties & Reverse Osmosis | Solutions Class 12

1. Osmosis and Osmotic Pressure

Osmosis: The spontaneous flow of solvent molecules through a Semi-Permeable Membrane (SPM) from a pure solvent (or lower concentration solution) to a higher concentration solution.

Osmotic Pressure ($\pi$): The excess pressure that must be applied to the solution side to just stop the flow of solvent molecules through the semi-permeable membrane.

Note: It prevents osmosis; it does not drive it.

2. Mathematical Expression (Van't Hoff Equation)

For dilute solutions, Osmotic Pressure is proportional to the Molarity ($C$) and Temperature ($T$).

$$ \pi = i \cdot C \cdot R \cdot T $$

Where:

  • $\pi$ = Osmotic Pressure (atm or bar)
  • $C$ = Molar Concentration ($n/V$ in mol/L)
  • $R$ = Gas Constant ($0.0821 \, L \cdot atm \cdot K^{-1} \cdot mol^{-1}$)
  • $T$ = Temperature (Kelvin)
  • $i$ = Van't Hoff Factor

3. Determination of Molar Mass ($M_2$)

Substituting $C = \frac{n_2}{V} = \frac{w_2}{M_2 \cdot V}$:

$$ M_2 = \frac{w_2 \cdot R \cdot T}{\pi \cdot V} $$

Why is this the best method for Polymers/Proteins?

  • Measured at room temperature (unlike boiling/freezing points which require heating/cooling).
  • Magnitude of $\pi$ is large even for very dilute solutions, making measurement easier and more accurate for macromolecules with high Molar Mass.

4. Types of Solutions

Type Condition Effect on Cell (RBC)
Isotonic $\pi_1 = \pi_2$ (Same Conc.) No change in size. (0.9% NaCl is isotonic with blood).
Hypertonic Solution $\pi >$ Cell $\pi$ Water flows out. Cell shrinks (Plasmolysis).
Hypotonic Solution $\pi <$ Cell $\pi$ Water flows in. Cell swells/bursts (Hemolysis).

5. Reverse Osmosis (RO)

If a pressure larger than the osmotic pressure ($P > \pi$) is applied to the solution side, the direction of solvent flow is reversed.

Pure solvent flows out of the solution through the SPM.

Application: Desalination of seawater to obtain potable water using cellulose acetate membranes.

Practice Quiz

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